World AIDS Day 2020
Volunteer scientists around the world have been searching for an HIV vaccine since the 1980s. World Health Organization says it has applications for 20 vaccines in development and that many clinical trials are underway.
Now they face a new dilemma: As scientists perfect a vaccine against HIV retroviruses, a race is already underway to find the vaccine against Coronavirus.
Trials are being carried out at the University of Oxford with a Coronavirus vaccine made from chimpanzee viruses. At the same time, Moderna is making another vaccine.
An article, published in npj Vaccines, examines the role of the Coronavirus in the development of an HIV vaccine and its effects on the human immune system.
The most effective vaccines are complete vaccines
These "complete vaccines" are "live and deadly vaccines."
The former, attenuated, have been very successful against polio, rotavirus, and measles, but have not been tested against HIV in humans. Using live retroviruses in vaccines raises safety concerns: Live HIV is too dangerous to be used in a vaccine, as HIV-1 has no antigenicity, so weakened HIV is not effective in triggering an immune response .
As Reuters points out, many of the world's most successful HIV vaccines rely on inactivated and weakened versions of the virus to make the vaccine. Because the vaccines only contain three HIV genes contained in weakened adenoviruses, study participants can become infected with respiratory diseases and become infected with HIV through vaccination.
This safety has important public health implications: If the COVID-19 vaccine causes serious side effects, experts fear that vaccine opponents who remain concerned about disease, even when the facts are not on their side, use the problem to spread your message and your program.
This could use the damage from the COVID-19 vaccine as an excuse to heighten the fears of anti-vaccine activists. Many of whom are already getting their messages across with no supporting facts.
We can foresee for the immediate future it is very clear: we will get vaccines against SARS and coronavirus 2, but we will not get the same against HIV.
In fact, we only know of one person, a young woman in her 20s, who received a dose of the COVID-19 vaccine. This after being placed in an Oxford AstraZeneca vaccine: Designed specifically to evaluate its safety and efficacy in people with AIDS, in early November. However, experience tells us that any hope for a rapid COVID-19 vaccine may prove inappropriate.
The results confirm the safety of the vaccine
They also provide important scientific information for developing new approaches. These would help promote pathways for vaccine development and delivery. Possible new vaccine modalities open: Messenger RNA vaccines. This accelerates the path to developing a vaccine against other viruses and potentially even other diseases.
Lastly, the results of the COVID-19 vaccine development should be applied to another challenge, such as the development of an HIV vaccine.
If the vaccine itself is available, what hope do you have that therapeutics will join the initiative to get an effective vaccine like this? Please follow us and tell us what you think about how you feel when a vaccine or a vaccine is available and what you think about the current state of development.
In other words, just because scientists haven't been able to develop an HIV vaccine for decades doesn't mean that researchers have to develop a COVID-19 vaccine. Even with this vaccine, there are other scientific and medical innovations that make Covid19 significantly less dangerous, if not curable. The MRNA vaccine will shorten the development and production time of the vaccine, shorten the production time of the vaccine, and give researchers more time to work on annual flu virus vaccines.
There is currently no licensed HIV vaccine on the market. Although there are several research projects they have tried to find an effective vaccine. But we have not seen successes in the development of the vaccine, although not for lack of effort.